Interplay between DNA supercoiling and transcription elongation
نویسندگان
چکیده
منابع مشابه
Interplay between DNA supercoiling and transcription elongation.
Transcription-coupled DNA supercoiling has been shown to be an important regulator of transcription that is broadly present in the cell. Here we review experimental work which shows that RNA polymerase is a powerful torsional motor that can alter DNA topology and structure, and DNA supercoiling in turn directly affects transcription elongation.
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ژورنال
عنوان ژورنال: Transcription
سال: 2014
ISSN: 2154-1264,2154-1272
DOI: 10.4161/trns.28636